Intercellular communication by EV

updated on September 16, 2023


JE.I The intercellular communication by extracellular vesicles: a specialized and diversified network in physiological and pathological conditions September 21
*Co-organized with:*

Extracellular vesicles (EVs) are nowadays recognized as fundamental elements in intercellular communication. They are a heterogeneous population of membrane-bounded vesicles that play important roles not only in cellular communication but also in preventing or promoting certain diseases, including infectious diseases, neurological disorders, metabolic alterations, and cancer. Techniques and innovative approaches for EVs isolation and characterization have been highlighted in this special event on EXTRACELLULAR VESICLES: THE NEW ERA OF THE INTERCELLULAR COMMUNICATION, organized by the Sapienza Dept of Biology and Biotechnology C.Darwin (Luciana Dini and Stefano Tacconi) in collaboration with EVITA (Annalisa Redeghieri), and divided in two symposia. Considering the extreme heterogeneity of the EVs and the difficulty of establishing standard analytical procedures, in the first symposium we will examine the new innovation research for a single and comprehensive vesicle analysis with four lectures on advanced techniques. The second symposium will be focused on the development and on the applications of innovative technologies for the study of extracellular vesicles. The event will be an opportunity to meet and discuss the state of the art and the prospects of technological research in the Extracellular Vesicles field.

September 21
09:00 - 10:30 Single and comprehensive vesicle analysis: the new innovation in the extracellular vesicle research JE.I.1 - TT.V.E
Chairs: Luciana DINI & Annalisa REDEGHIERI, Sapienza University of Rome
JE.I.1.1 TT.V.E.1	Paolo BERGESE - CV Università degli Studi di Brescia, IRIB - CNR, CSGI 6 + 1 out-of-the-box problems in measuring EVs
JE.I.1.2 TT.V.E.2	Dario BRAMBILLA - CV SCITEC, CNR, Milano Reversible aptamer-directed immobilization of antibodies and its application in extracellular vesicles separation
JE.I.1.3 TT.V.E.3	Carlo MORASSO - CV Istituti Clinici Scientifici Maugeri, Pavia Biochemical profiling of endogenous nanoparticles by Raman Spectroscopy in breast cancer
JE.I.1.4 TT.V.E.4	Giacomo PARISI - CV Sapienza University of Rome Unveiling Extracellular Vescicles diverse morphology with Cryo-Electron Microscopy

11:30 - 13:00 Application of innovative technologies to the study of extracellular vesicles JE.I.2 - TT.VI.G
Chairs: Luciana DINI & Annalisa REDEGHIERI, Sapienza University of Rome
JE.I.2.1 TT.VI.G.1	Roberto FRIGERIO - CV CNR Integrated diagnostic workflow for blood and urinary Extracellular Vesicles by Membrane Sensing Peptides and digital detection
JE.I.2.2 TT.VI.G.2	Aurora MANGOLINI - CV LABION/FDG SPRi based biosensor for the detection of extracellular vesicles as rehabilitation biomarkers
JE.I.2.3 TT.VI.G.3	Carolina PABA University of Trieste Lipid bilayer fluidity and degree of order regulates small EVs adsorption on model cell membrane
JE.I.2.4 TT.VI.G.4	Giada ROSSO - CV Gruppo Cauda Fully artificial extracellular vescicles: a biomimicking strategy towards effectvie theranostic tools in nanomedicine
JE.I.2.5 TT.VI.G.5	Diana VARDANYAN - CV CNR AFM of single vesicles: a multiparametric morpho quantitative analysis
JE.I.2.6 TT.VI.G.6	Deborah POLIGNANO - CV ISS Effects of intracellular pathway inhibitors on the secretion, protein, and lipid composition of fluorescent Bodipy sEV